I have a carta di sorggiorno and a Ghanaian passport.

Can i go to Germany and work?

Please go through existing threads in this forum: https://www.expat.com/forum/viewforum.php?id=322

This question has been answered many times.

All work permits are national, meaning they are valid only for the country that issued them.
To work in Germany, you need a German work permit.

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