Hello,
I've been perusing all the flights to Cuenca from Richmond, VA. It seems all of those require an overnight stay in Quito. However, interestingly, the airfare from Richmond to Quito is the same as to Cuenca! Many of those sites (CheapoAir, Expedia, etc.) aren't set up for arranging one night stay in Quito and the remainder of the stay in Cuenca if choosing hotel + flight. Any advice or recommendations?